DISC-3D: DUAL-HYDROGEL SYSTEM ENHANCES OPTICAL IMAGING AND ENABLES CORRELATIVE MASS SPECTROMETRY IMAGING OF INVADING MULTICELLULAR TUMOR SPHEROIDS

DISC-3D: dual-hydrogel system enhances optical imaging and enables correlative mass spectrometry imaging of invading multicellular tumor spheroids

Abstract Multicellular tumor spheroids embedded in collagen I matrices are common in vitro systems for the study of solid tumors that reflect the physiological environment and complexities of the in vivo environment.While collagen I environments are physiologically relevant and permissive of cell invasion, studying spheroids in such hydrogels prese

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Transcatether closure of an atrial redirection baffle leak

We present the case of a woman born with transposition of the Georgia great arteries, who was surgically repaired with the Mustard technique.Because of interatrial shunting, she was brought to the cardiac catheterization laboratory for device closure.Matrix-array 3D transesophageal echocardiography enabled visualization Ferrite Bars of both baffle

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Shareholder heterogeneity, financing constraints, and organizational resilience: Mixed-ownership reform in Chinese private enterprises

Private enterprise development encounters numerous challenges.China encourages state-owned enterprises to acquire equity stakes in private enterprises, thereby facilitating development of private enterprises through reverse mixed-ownership reform.To test the effectiveness of this approach, we focus on the impact of state-owned equity on the organiz

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